But what is titanium dioxide, exactly? Here's what you need to know about this popular food additive — including what products it's used in and whether it's safe to consume.

For a review published in 2023 in the journal Environmental Pollution, researchers examined E171 as a possible factor promoting obesity-related metabolic disorders. Because gut microbiota play an important role in immune function maintenance and development, and because titanium dioxide as a food additive has been shown to alter gut microbiota, researchers wanted to review “the dysregulations along the gut microbiota-immune system axis after oral TiO2 exposure compared to those reported in obese or diabetic patients, and to highlight potential mechanisms by which foodborne TiO2 nanoparticles may increase the susceptibility to develop obesity-related metabolic disorders.” The study authors discovered recurrent changes in the gut microbiota composition when exposed to titanium dioxide nanoparticles, with an imbalance of intestinal symbiotic microbiota. These changes and imbalances were also reported and played a role in the development of obesity, the authors wrote. This highlights “foodborne TiO2 nanoparticles as an endocrine disruptor-like chemical promoting obesity-related disorders,” the authors concluded.

Titanium dioxide is typically micronized and coated for use in cosmetics products. The micronizing makes this somewhat heavy-feeling ingredient easier to spread on skin, plus a bit more cosmetically elegant. Micronized titanium dioxide is much more stable and can provide better sun protection than non-micronized titanium dioxide.

The committee could not finalize the assessment of some other flavoring agents, requiring further information. JECFA highlighted the importance of receiving complete data submissions from the sponsors for conducting the safety evaluation.

Lithopone 30% is a perfect alternative to titanium dioxide in all natural and synthetic pigmented elastomers, as it is non-abrasive and extremely acid resistant. 

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Further outstanding properties of Lithopone are its high lightness, neutral white colour and its diffuse reflectance in the near UV range.

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Lithopone was discovered in the 1870s by DuPont. It was manufactured by Krebs Pigments and Chemical Company and other companies. The material came in different seals, which varied in the content of zinc sulfide. Gold seal and Bronze seals contain 40-50% zinc sulfide, offering more hiding power and strength. Although its popularity peaked around 1920, approximately 223,352 tons were produced in 1990. It is mainly used in paints, putty, and in plastics.

Other food products that list titanium dioxide are Lucerne cottage cheese, Beyond Meat's chicken plant-based tenders, Great Value ice cream and Chips Ahoy! cookies.

Below 10% substitution, 1 kg of TiO2 should be replaced by 1 kg of lithopone supplier 30%.  

Titanium dioxide is predominantly used as a pigment in products such as paints, coatings, plastics, food, cosmetics, and paper. The ability of TiO2 to scatter light and provide a white color makes it an essential ingredient in achieving high-quality finishes in these applications. However, the production of titanium dioxide can be complex and costly, given that it involves raw materials such as ilmenite and rutile, as well as advanced processing technologies. Manufacturers are continuously striving to optimize costs without compromising quality, making the search for affordable suppliers a top priority for many businesses.